Infrastructure
Lee County’s infrastructure is built to support the movement of goods, the growth of industry, and the long-term success of employers. Positioned along the Mississippi River, the county offers established riverfront logistics, integrated transportation networks, and reliable utility systems that serve both existing businesses and new investments. Fort Madison and Keokuk anchor a coordinated, county-wide approach to infrastructure planning, workforce development, and business support. Through strong public-private collaboration led by LCEDG and regional partners, Lee County delivers site-ready assets, streamlined permitting, and the dependable services companies need to operate and scale with confidence.
Transportation & Infrastructure
Road
Lee County is served by two four-lane highways: US 218 (the Avenue of the Saints) running from Saint Louis, Missouri to Saint Paul, Minnesota; and US Highway 61, which runs through the eastern part of the county.
Maps
Lee County - Driving Distances Map Lee County - Transportation Map Southeast Iowa - Regional Highways Map
Rail
Lee County is serviced by the main rail line of Burlington Northern Santa Fe (BNSF) Railway, the largest freight rail transportation network in North America, providing a vital link to the global supply chain.
Maps
River
The Mississippi River provides transportation for Lee County industries from Saint Paul, Minnesota to the Gulf of Mexico. Lee County also has access to three inter-modal port terminals.